New organoselenium compounds active against pathogenic bacteria, fungi and viruses

…, K Kołodziejczyk, E Piasecki, J Młochowski

Index: Pietka-Ottlik, Magdalena; Wojtowicz-Mlochowska, Halina; Kolodziejczyk, Katarzyna; Piasecki, Egbert; Mlochowski, Jacek Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 10 p. 1423 - 1427

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Citation Number: 54

Abstract

Different N-substituted benzisoselenazol-3 (2H)-ones, analogues of ebselen were designed as new antiviral and antimicrobial agents. We report their synthesis, chemical properties as well as study on biological activity against broad spectrum of pathogenic microorganisms (Staphylococcus aureus, Staphylococcus simulans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Candida albicans, Aspergillus niger) and viruses ( ...