Tetrahedron

Approach to the perhydroisoindole system in cytochalasin B

JM Lemmens, L Thijs, B Zwanenburg

Index: Lemmens; Thijs; Zwanenburg Tetrahedron, 1984 , vol. 40, # 17 p. 3331 - 3337

Full Text: HTML

Citation Number: 4

Abstract

The synthesis of the perhydroisoindole systems 17a, b, 22 and 23 is described using the following sequence of reactions. Diels-Alder cycloaddition of silyloxydienes 4 with methyl acrylate leads, after methanolysis, to cyclohexenonecarboxylates 6, subsequent ...