Interactions of various metal ions with pyridine tethered 1, 4-naphthoquinone derivatives (1– 4) are studied by fluorescence spectroscopy. The fluorescence emission of 2-(pyridine-2-yl- methylamino) naphthalene-1, 4-dione (1) is influenced by various metal ions and show highly selective fluorescence emission with Mn2+ ions and fluorescence ON and OFF states can be generated at different concentrations of Mn2+ ions. Sequential addition of Ni2+ ...