A Polycomponent Metal??Catalyzed Aliphatic, Allylic, and Benzylic Fluorination

S Bloom, CR Pitts, DC Miller, N Haselton…

Index: Bloom, Steven; Pitts, Cody Ross; Miller, David Curtin; Haselton, Nathan; Holl, Maxwell Gargiulo; Urheim, Ellen; Lectka, Thomas Angewandte Chemie, International Edition, 2012 , vol. 51, # 42 p. 10580 - 10583,4 Angewandte Chemie, 2012 , vol. 124, # 42 p. 10732 - 10735,4

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Citation Number: 101

Abstract

The selective incorporation of fluorine into organic molecules has advanced in dramatic ways over the last 30 years.[1] Although arene [2] and alkyne [3] fluorination using metal catalysis has received much attention, the corresponding methods for metal-catalyzed alkane fluorination remain only a promising goal [Eq.(1)].[4] To date, the most notable methods for alkane fluorination [5] involve the use of stoichiometric quantities of difficult-to- ...