Abstract: EtAlCl, catalyzes the ene reactions of a-substituted acrylate esters with trans 1, 2-di- and trisubstituted alkenes at 25 OC. The reactions are regio-and stereoselective. The ester group adds endo and a hydrogen is transferred selectively from the alkyl group syn to the vinylic hydrogen. Methyl a-chloroacrylate, a-bromoacrylate, acetamidoacrylate, and methacrylate, ethyl a-bromomethylacrylate, and dimethyl itaconate were explored. Ene ...
