In 1996, we reported the synthesis of (+)-xestoquinone (3) (Figure [1] ) using an asymmetric intramolecular palladium-catalyzed polyene cyclization (4 → 5, Scheme [1] ) as the key step. [6] Due to their similar scaffolds, we decided to use this key reaction towards the synthesis of viridin (Scheme [1] ). Functional group interconversions (FGI) of 1 provided 6 that would be the product from an asymmetric Pd-catalyzed polyene cyclization from triflate 7. Further disconnection ...
![1-[(trimethylsilyl)oxy]-4-(trimethylsilyl)-3-butyne Structure](https://image.chemsrc.com/caspic/290/58434-99-4.png)
