Tetrahedron letters

Synthese stereospecifique de l'ester methylique de l'acide amino-2 oxo-8 epoxy-9, 10 decanoique (2s, 9r) N-protege.

R Jacquier, R Lazaro, H Raniriseheno, P Viallefont

Index: Jacquier, R.; Lazaro, R.; Raniriseheno, H.; Viallefont, P. Tetrahedron Letters, 1984 , vol. 25, # 48 p. 5525 - 5528

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Citation Number: 13

Abstract

Abstract The first stereospecific synthesis of methyl (2S, 9R) N-tBOC 2-amino 8-oxo 9, 10- epoxydecanoate has been carried out by using two steps allowing a chirality control: a stereospecific alkylation of the Schiff base 4 and Sharpless epoxidation of the allylic alcohol 6.