A Synthetic Study of Atropurpuran: Construction of a Pentacyclic Framework by an Intramolecular Reverse??Electron??Demand Diels–Alder Reaction

…, A Sasaki, N Egashira, S Kobayashi

Index: Suzuki, Takahiro; Sasaki, Aya; Egashira, Naoki; Kobayashi, Susumu Angewandte Chemie - International Edition, 2011 , vol. 50, # 39 p. 9177 - 9179

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Citation Number: 19

Abstract

Aconitum is a genus of flowering plants that produce a variety of poisons and compounds of medicinal importance. The fascinating bioactivities of these compounds arise from C19 and C20 diterpene alkaloids, such as aconitine, hetisine, atisine, and kobusine.[1] Isolation of non-alkaloidal diterpenes from the genus Aconitum, however, has rarely been reported.[2] In 2009, Wang and co-workers reported the isolation of the structurally unique non-alkaloidal ...