Tetrahedron Letters

A new intramolecular barbier reaction of N-(2-iodobenzyl) phenacylamines: A convenient synthesis of 1, 2, 3, 4-tetrahydroisoquinomn-4-ols

M Kihara, M Kashimoto, Y Kobayashi, S Kobayashi

Index: Kihara, Masaru; Kashimoto, Minoru; Kobayashi, Yoshimaro; Kobayashi, Shigeru Tetrahedron Letters, 1990 , vol. 31, # 37 p. 5347 - 5348

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Citation Number: 21

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... 4-Phenyl-1,2,3,4-tetrahydroisoquinolin-4-ols were prepared by an intramolecular Barbier reaction of N-(2-iodobenzyl)phenacylamines with butyllithium in good yields. ... M.Kihara, Y. Kobayashi, and M.Kashimoto, unpublished results. ... J. Chem. Soc. (P 1) (1989), p. 2223 ...

~17%

~71%

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