Medicinal Chemistry Research

Novel 2-pyrazoline derivatives as potential anticonvulsant agents

S Bhandari, AC Tripathi, SK Saraf

Index: Bhandari, Shradha; Tripathi, Avinash C.; Saraf, Shailendra K. Medicinal Chemistry Research, 2013 , vol. 22, # 11 p. 5290 - 5296

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Citation Number: 7

Abstract

Abstract A series of new 2-pyrazoline derivatives has been synthesized by reacting 3- (substituted-phenyl)-1-pyridin-2-yl-propenones using two routes one using thiosemicarbazide and the other by hydrazine hydrate. The chemical structures were established by IR, Mass, 1 H-NMR, 13 C-NMR spectroscopic data, and elemental analysis. The anticonvulsant activity of the synthesized compounds was evaluated by the “maximal ...