In connection with the investigation of the effect of acyl substituents on the therapeutic activity of sulfonamide-related materials, acyl derivatives of sulfanilamide, sulfathiazole, 2- amino-5-thiazolyl-pnitrophenyl sulfide, 2 and 2-amjno-5-thiazolyl-pnitrophenyl sulfoneL were required (Tables I and 11). Synthesis was accomplished conveniently by reaction of the amino compound with the appropriate anhydride r (diglycolic, thiodiacetic, ...