Products of Reaction Between Hetereno [a]-2, 3-dihydro-2, 3-pyrrolediones and Aryl-Or Heterylamines and Their Pharmacological Activity

…, GA Aleksandrova, OS Kudinova, SV Kol'tsova…

Index: Mashevskaya; Makhmudov; Aleksandrova; Kudinova; Kol'tsova; Goleneva; Maslivets Pharmaceutical Chemistry Journal, 2000 , vol. 34, # 12 p. 640 - 643

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Citation Number: 1

Abstract

We established earlier that 3-aroyl-1, 2, 4, 5-tetrahydropyrrolo [1, 2-a] quinoxaline-and 3- aroyl-1, 2-dihydro-4H-pyrrolo-[5, 1-c][1, 4] benzoxazine-1, 2, 4-triones exhibit antimicrobial and analgesic activity [1]. It seemed of interest to modify their structure by introducing various heterocycles into the molecule for the above-indicated compounds and to study the chemical behavior of the products obtained and their properties, by investigating the effect ...