Acetylation of 5-amino-1 H-[1, 2, 4] triazole revisited

…, E Masiukiewicz, B Rzeszotarska

Index: Dzygiel, Anetta; Masiukiewicz, Elzbieta; Rzeszotarska, Barbara Journal of agricultural and food chemistry, 2002 , vol. 50, # 6 p. 1383 - 1388

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Citation Number: 13

Abstract

The products of the acetylation reactions of the common herbicide 5-amino-1 H-[1, 2, 4] triazole were investigated using HPLC, GC-MS, 1H NMR, and FTIR spectroscopy. The conventional annular monoacetylation procedures with acetyl chloride are not regioselective and furnish a mixture of isomers. Traditional diacetylation in neat acetic anhydride under reflux produces a mixture of di-, mono-, and triacetylated derivatives. By using equivalent ...