Palladium-catalyzed cyclization of 1-iodo-substituted 1, 4-, 1, 5-, and 1, 6-dienes as well as of 5-iodo-1, 5-dienes in the presence of carbon monoxide

E Negishi, S Ma, J Amanfu, C Copéret…

Index: Negishi; Ma; Amanfu; Coperet; Miller; Tour Journal of the American Chemical Society, 1996 , vol. 118, # 25 p. 5919 - 5931

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Citation Number: 86

Abstract

A series of ω-alkene-containing alkenyl iodides were prepared via (a) various allyl-, homoallyl-, and higher ω-alkenylmetalation reactions of alkynes involving Zn, Al-Zr, Zn-Zr, and Cu,(b) trans-hydroalumination and Cu-catalyzed trans-carbomagnesiation of propargyl alcohols, and (c) Zr-promoted alkyne-alkene coupling. Various factors affecting three cyclic acylpalladation (Types I-III Ac-Pd) and three cyclic carbopalladation (Types I-III C-Pd) ...