Conformational studies by dynamic NMR. 50. Atropisomerism in hindered naphthyl sulfoxides: structure, stereodynamics, and chiral resolution

D Casarini, E Foresti, F Gasparrini…

Index: Casarini, D.; Foresti, E.; Gasparrini, F.; Lunazzi, L.; Macciantelli, D.; et al. Journal of Organic Chemistry, 1993 , vol. 58, # 21 p. 5674 - 5682

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Citation Number: 41

Abstract

Like configurational enantiomers, conformational enantiomers too can be isolated, provided the instrumentation for conducting low-temperature chiral chromatographic (LT-Chir HPLC) separations is available. In favorable circumstances, assignment of the absolute configuration can be achieved simultaneously if the same low temperature is maintained in the cell of a CD spectrometer that is connected to the cooled chiral column. It is of ...