Synthesis and chemistry of cyclic sulfoximines

K Schaffner-Sabba, H Tomaselli, B Henrici…

Index: Schaffner-Sabba,K. et al. Journal of Organic Chemistry, 1977 , vol. 42, p. 952 - 958

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Citation Number: 24

Abstract

19 dergo acylation on carbon. Inverse addition of the lithio derivative of 10 to 1 equiv of methyl chloroformate gave in good yield, the ester 14, which could be aminated with ammonia or methylamine in good yields providing the amides 15. Cyclization of 15a with sodium methoxide gave the 1, 2, 4-thiadiazinedione 1-oxide 16 in 47% yield along with 2- 5% of the methanolysis product 17.'" Attempted cyclization of 15b with sodium methoxide ...