Tetrahedron

Carbohydrate-based templates for synthetic vaccines and drug delivery

RP McGeary, I Jablonkai, I Toth

Index: McGeary, Ross P; Jablonkai, Istvan; Toth, Istvan Tetrahedron, 2001 , vol. 57, # 41 p. 8733 - 8742

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Citation Number: 36

Abstract

Methyl tetra-O-allyl, and tetra-O-[2-(tetrahydro-2H-pyranyl) oxy.-3-oxapentyl glucosides, and tetra-O-(cyanoethyl) galactosyl azide were converted into derivatives containing linkers with terminal carboxylic acid functionalities at the anomeric position and bearing four arms with phthaloyl-or BOC-protected terminal amino groups. These molecules were suitable for use in solid-phase peptide synthesis and for the preparation of dendrimers containing multiple ...