Intramolecular versus intermolecular induction of helical handedness in pyridinedicarboxamide oligomers

V Maurizot, C Dolain, I Huc

Index: Maurizot, Victor; Dolain, Christel; Huc, Ivan European Journal of Organic Chemistry, 2005 , # 7 p. 1293 - 1301

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Citation Number: 35

Abstract

Abstract A new convergent synthetic scheme has been developed to prepare oligoamides of 2, 6-diaminopyridine and 4-decyloxy-2, 6-pyridinedicarboxylic acid. These compounds adopt stable single helical conformations in solution. NMR and circular dichroism studies show that intramolecular and intermolecular chiral induction of handedness in these helices is possible. Intramolecular induction is effected by attaching a single chiral group to the ...