Synthèse et études structurales de nouveaux complexes polyhydroxamiques du fer (III) potentiellement utilisables en imagerie par résonance magnétique nucléaire. I: …

…, MNV Duong, J Courtieu, A Gaudemer…

Index: Chaubet; Nguyen Van Duong; Courtieu; Gaudemer; Gref; Crumbliss Canadian Journal of Chemistry, 1991 , vol. 69, # 7 p. 1107 - 1116

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Citation Number: 8

Abstract

With a view to preparing stable iron (III) complexes that can be used as contrast agents in magnetic resonance imaging, we have prepared a series of dihydroxamates that are analogs of rhodotorulic acid, a natural siderophore. These new ligands have been synthesized by condensation of 2, 6-pyridine dicarboxylic acid chloride with protected N- aminopropyl-N-acetylhydroxylamine. In addition to the ligand derived from 2, 6-pyridine ...