KF/Al 2 O 3 and PEG-400 as a recyclable medium for the selective α-selenation of aldehydes and ketones. Preparation of potential antimicrobial agents

FN Victoria, CS Radatz, M Sachini, RG Jacob, G Perin…

Index: Victoria, Francine Novack; Radatz, Catia S.; Sachini, Maraisa; Jacob, Raquel G.; Perin, Gelson; da Silva, Wladimir P.; Lenardao, Eder J. Tetrahedron Letters, 2009 , vol. 50, # 49 p. 6761 - 6763

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Citation Number: 28

Abstract

2-Phenylseleno aldehydes and ketones were selectively obtained using solid-supported catalyst (KF/Al2O3) and PEG-400 as clean, recyclable medium in good to excellent yields. The method was applied in the preparation of highly functionalized 2-phenylseleno citronellal and citronellol, potential bactericide agents. The catalytic system KF/Al2O3 and PEG-400 can be re-used for four times without previous treatment.