Tetrahedron: Asymmetry

Enantioselective inclusion of chiral alkyl aryl sulfoxides in a supramolecular helical channel consisting of an enantiopure 1, 2-amino alcohol and an achiral carboxylic …

Y Kobayashi, K Kodama, K Saigo

Index: Kobayashi, Yuka; Soetrisno; Kodama, Koichi; Saigo, Kazuhiko Tetrahedron Asymmetry, 2008 , vol. 19, # 3 p. 295 - 301

Full Text: HTML

Citation Number: 15

Abstract

The enantioselective clathrate formation of alkyl aryl sulfoxides 4 was achieved with dissymmetric one-dimensional helical channels created in two-component hosts consisting of (1R, 2S)-2-amino-1, 2-diphenylethanol 1 and an achiral carboxylic acid, p-tert- butylbenzoic acid 2, or 2-anthraquinonecarboxylic acid 3. X-ray crystallographic analyses showed that the host framework (1R, 2S)-1· 3 in the single crystal of a clathrate with methyl ...