Tetrahedron: Asymmetry

Selectivity of Daucus carota roots and baker's yeast in the enantioselective reduction of γ-nitroketones

D Scarpi, EG Occhiato, A Guarna

Index: Scarpi, Dina; Occhiato, Ernesto G.; Guarna, Antonio Tetrahedron Asymmetry, 2005 , vol. 16, # 8 p. 1479 - 1483

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Citation Number: 21

Abstract

The enantioselective reduction of a series of aromatic γ-nitroketones was achieved by using Daucus carota roots in water, which afforded the corresponding (S)-alcohols with ees ranging from 73% to 100%. A comparison of these results with the data obtained by reducing the same substrates with baker's yeast resulted in D. carota always being more enantioselective than baker's yeast, although a lower number of substrates were reduced. ...