Synthesis of 2-(2-hydroxyalkylidene) cyclopentanones and their bio-antimutagenic activity

R Iriye, A Nakamura, M Takeshita

Index: Iriye; Nakamura; Takeshita Bioscience, biotechnology, and biochemistry, 1995 , vol. 59, # 3 p. 401 - 407

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Citation Number: 2

Abstract

2-(2-Hydroxyalkylidene) cyclopentanones (1) and 5-(2-hydroxyoctylidene)-2- cyclopentenone (2) were synthesized by the aldol reaction of cyclopentanone-enolate (3)/cyclopentenone-enolate (19) with 2-bromoalkanals (4)/2-bromooctanal (4c) and