Abstract By the promotion of chlorotrimethylsilane, asymmetric Michael reaction of the chiral enamines (2) of α-alkyl β-keto esters (1) with methyl vinyl ketone and ethyl acrylate proceeded to afford, after hydrolysis, either enantiomer of the corresponding adducts (4) in a good enantioselectivity.
![N-[2-(ethoxycarbonyl)-1-methylprop-1-enyl]-L-valine tert-butyl ester Structure](https://image.chemsrc.com/caspic/475/104372-11-4.png)
