Chemistry letters

Oxidations of DihydroxyaLkanoates to Vicinal Tricarbonyl Compounds with a 4-BzoTEMPO-Sodium Bromite System or by Indirect Electrolysis Using 4-BzoTEMPO and …

T Inokuchi, P Liu, S Torii

Index: Inokuchi, Tsutomu; Liu, Ping; Torii, Sigeru Chemistry Letters, 1994 , # 8 p. 1411 - 1414

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Citation Number: 23

Abstract

An efficient access to vicinal dioxoalkanoates, one of structural elements of potent competitive inhibitors of hydrolytic enzyme, from 2, 3-dihydroxyalkanoates has been developed, which features an one-step procedure with a mild oxidizing system using recyclable 2, 2, 6, 6-tetramethylpiperidine-1-oxyl in combination with NaBrO 2· 3H 2 O or electrogenerated active bromine species as a real oxidant.