... (5) The regioselective ring opening of the epoxides is shown by the chemical shifts and coupling constants of the protons ... (6) Miller, J. A.; Wood, H. C. S. British Patent 1121 307, 1968. Page 3. 1584 Journal of Medicinal Chemistry, 1983, Vol. 26, No. 11 Evans et al. R' I ” z ON ...