Synthesis and sedative-hypnotic effects of N3-allyl-and N1-allyl-5, 6-substituted 2-thiouracil derivatives in mice.

M Draminski, K Turski, Y Tateoka, T Kimura…

Index: Turski, K.; Draminski, M. Polish Journal of Chemistry, 1992 , vol. 66, # 10 p. 1591 - 1596

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Citation Number: 8

Abstract

Twenty four thiouracil derivatives, including N 3-allyl-(19) and N 1-allyl-2-thiouracil (20) were synthesized and their pharmacological effects [sedative-hypnotic activity (loss of righting reflex and spontaneous activity), convulsant activity, effect on pentobarbital (PB)-induced