Acyl tetramic acids. 6. Synthesis of 3-dienoyl tetramic acids related to streptolydigin and tirandamycin

VJ Lee, AR Branfman, TR Herrin…

Index: Lee; Branfman; Herrin; Rinehart Jr. Journal of the American Chemical Society, 1978 , vol. 100, # 13 p. 4225 - 4236

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Citation Number: 62

Abstract

Abstract: 3-Dienoyl tetramic acids related to the antibiotics tirandamycin and streptolydigin have been prepared via intramolecular CIaisen condensation and via acylation of 2, 4- pyrrolidiones. The spectroscopic properties of these novel analogues, which are described, provide excellent models for like properties of the antibiotics.