Journal of the American Chemical Society

The Synthesis of D-, L-and DL-2-amino-2-carboxyethyl 2-Guanidinoethyl Hydrogen Phosphate (Lombricine) and the Identity of the Natural Compound with the D …

IM Beatty, DI Magrath

Index: Beatty,I.M.; Magrath,D.I. Journal of the American Chemical Society, 1960 , vol. 82, p. 4983 - 4989

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Citation Number: 8

Abstract

Thoai and Robin2 in 1954 reported the isolation from earthworms (Lumbricus terrestris) of a new phosphorus-containing guanidine derivative, lombricine, to which, from evidence based on elementary analysis, a study of the functional groups present and paper chromatographic identification of the products of acid hydrolysis, they allocated the structure, 2-amino-2- carboxyethyl 2-guanidinoethyl hydrogen phosphate (I). The amount of material isolated ...