A Novel One??Pot Synthesis of 2??Aryl??4 (3 H)??Quinazolinones Using Room Temperature Ionic Liquid as Reaction Medium as well as Promoter

TM Potewar, RN Nadaf, T Daniel, RJ Lahoti…

Index: Potewar; Nadaf; Daniel, Thomas; Lahoti; Srinivasan Synthetic Communications, 2005 , vol. 35, # 2 p. 231 - 241

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Citation Number: 59

Abstract

Abstract An efficient one??pot synthesis of 2??aryl??4 (3 H)??quinazolinones from 2??amino benzamides and substituted benzoyl chlorides in a room temperature ionic liquid is described. Compared with the classical reaction conditions, this new synthetic method has the advantages of recyclability of ionic liquid, very good to excellent yields (78–92%), the absence of hazardous and expensive catalysts, and easy workup procedures giving rise ...