Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease

SW Kaldor, VJ Kalish, JF Davies…

Index: Journal of Medicinal Chemistry, , vol. 40, # 24 p. 3979 - 3985

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Citation Number: 429

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. The syntheses of compounds 11a−c are summarized in Scheme 1. The unnatural amino acids 2a and 2b were prepared from N-Cbz-l-serine by formation of the corresponding ...

Viracept (nelfinavir mesylate, AG1343): a potent, orally bio...

[Kaldor, Stephen W.; Kalish, Vincent J.; Davies II, Jay F.; Shetty, Bhasker V.; Fritz, James E.; Appelt, Krzysztof; Burgess, Jeffrey A.; Campanale, Kristina M.; Chirgadze, Nickolay Y.; Clawson, David K.; Dressman, Bruce A.; Hatch, Steven D.; Khalil, Deborah A.; Kosa, Maha B.; Lubbehusen, Penny P.; Muesing, Mark A.; Patick, Amy K.; Reich, Siegfried H.; Su, Kenneth S.; Tatlock, John H. Journal of Medicinal Chemistry, 1997 , vol. 40, # 24 p. 3979 - 3985]