Acylation of cellular and viral proteins by fatty acids has recently been recognized as an important post-translational protein modification. In some cases such protein acylation may be neces-sary for viral replication and retroviral induced events such as tumorigenesis and immunosuppression. N-Myristoylation of the N-terminal glycine of various cellular, oncogenic and viral proteins appears to be a particularly important modification and is the ...
