Synthesis and antileukemic activity of (.+-.)-20-deoxyaminocamptothecin analogues.

江島明男， 寺沢弘文， 杉森正道， 大薄悟…

Index: Chemical and Pharmaceutical Bulletin, , vol. 37, # 8 p. 2253 - 2255

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Citation Number: 13

Abstract

... lactone) cm—1; 1H—NMR (CDCIB) d: 6.42 (1H, s, arom—H)]. Azide 6 was deketalized with 802 aqueous trifluoroacetic acid (TFA) at 0°C to afford tricyclic ketone 7 as an oil is 952 yield [IR (film): 2100 (N3) cm"1]. (M 20 H © 1989 Pharmaceutical Society of ... 2254 Vol. 37, No. ...