Tetrahedron

Design and synthesis of new krn7000 analogues

M Sun, Y Wang, XS Ye

Index: Sun, Man; Wang, Yuhang; Ye, Xin-Shan Tetrahedron, 2013 , vol. 69, # 35 p. 7438 - 7447

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Citation Number: 5

Abstract

Abstract Presented by CD1d protein, KRN7000, a potent synthetic α-galactosylceramide, is known to stimulate the iNKT cells to produce different bioactive cytokines. Six new KRN7000 analogues, in which the amide bond in KRN7000 is replaced with O, NH, or ester groups