3-Chloro-1-azaallylic anions, generated by deprotonation of a-chloro ketimines with lithium diisopropylamide, reacted with ketones and aldehydes to produce 2-imidoyloxiranes (a, P- epoxy ketimines). This novel aza-Darzens-type condensation allows a-chloro ketones to condense with carbonyl compounds via protection as a-chloro ketimines. The aza-Darzens- type reaction with benzophenones as carbonyl substrate proceeded via a Favorskii-like ...
