Journal of Chemical Research

Vicinal benzo [b] thiophene-5, 6-dicarboxaldehyde in heterocyclic synthesis: a reagent for fluorescence determination of amino acids

MA El-Borai, HF Rizk

Index: El-Borai, Mohamed A.; Rizk, Hala F. Journal of Chemical Research, 2009 , # 5 p. 326 - 328

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Abstract

Benzo [b] thiophene-5, 6-dicarboxaldehyde reacts with dibenzyl ketone, thiodiacetic acid dimethyl ester, hydrazine, p-toluidine, p-aminoacetophenone and nitromethane to give the corresponding seven, six and five-membered rings condensed to benzo [b] thiophene. Reaction of benzo [b] thiophene-5, 6-dicarboxaldehyde with p-toluidine in the presence of 2- mercaptoethanol gives highly fluorescent compounds. Also, benzo [b] thiophene-5, 6- ...