Synthesis and antiarrhythmic activity of 3-alkoxycarbonylamino-s-acylaminostilbenes

…, A Stark, L Zenker, D Loman, H Poppe, R Barch

Index: Skoldinov; Kaverina; Gritsenko; Lyskovtsev; Wunderlich; Stark; Zenker; Loman; Poppe; Barch Pharmaceutical Chemistry Journal, 1996 , vol. 30, # 3 p. 166 - 169

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Abstract

A number of active antidepressants, such as imizine and clomipramine, belong to the class of 5-aminoalkyliminodibenzyls. At the same time, some of the corresponding 5-aminoacyl derivatives of iminodibenzyl exhibit no psychotropic properties but produce a cardiotropic action [I]. In the search for new compounds possessing antiarrhythmic properties and producing no central-excitation or sedative effect, we have synthesized and characterized ...