Identification and characterization of pectenotoxin (PTX) 4 and PTX7 as spiroketal stereoisomers of two previously reported pectenotoxins

K Sasaki, JLC Wright, T Yasumoto

Index: Sasaki; Sasaki, Katsunori; Wright; Wright, Jeffrey L. C.; Yasumoto; Yasumoto, Takeshi Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2475 - 2480

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Citation Number: 86

Abstract

Pectenotoxins (PTXs) isolated from the scallop Patinopecten yessoensis were shown to be involved in an episode of diarrhetic shellfish poisoning (DSP). A total of eight analogues (PTX1-PTX7 and PTX10) have been isolated to date, and the structures of four of these analogues (PTX1, PTX2, PTX3, and PTX6) have already been elucidated. Here, we report the characterization of PTX4 and PTX7 as 7-epi-PTX1 and 7-epi-PTX6, respectively, on ...