Journal of the American Chemical Society

Tetrahydropyranyl amino alcohols

GH Harnest, A Burger

Index: Harnest; Burger Journal of the American Chemical Society, 1943 , vol. 65, p. 370

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Citation Number: 6

Abstract

Morphine has often been interpreted as a tutiary amino alcohol derived from the various polycyclic ring systems which can be discerned in the molecule of the alkaloid. 2 The study of condensed cyclic aryl ethers3 and sulfides4 carrying alkamine side-chains has been based on the assumption that these groups may be responsible, in part, for the analgesic action of morphine. A simplification of this principle mould lead to monocyclic ethers ...