Host-guest complexation. 23. High chiral recognition of amino acid and ester guests by hosts containing one chiral element

DS Lingenfelter, RC Helgeson…

Index: Lingenfelter, David S.; Helgeson, Roger C.; Cram, Donald J. Journal of Organic Chemistry, 1981 , vol. 46, # 2 p. 393 - 406

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Citation Number: 238

Abstract

The chiral recognition properties of ten enantiomerically pure hosts toward the enantiomers of six different amino acids and their methyl esters have been examined. The hosts possessed the general structure (A), D-(OEOEO) zE, in which D is the chiral 1, l'-dinaphthyl group substituted in the 2, 2'-positions with oxygens (0) attached through ethylene groups (E) to form a macrocycle. The A groups are substituted in the 3, 3'-positions of the 1, l'- ...