Free radical macrocyclizations from steroid-derived precursors

DM Scott, AT McPhail, NA Porter

Index: Scott, Daniel M.; McPhail, Andrew T.; Porter, Ned A. Journal of Organic Chemistry, 1993 , vol. 58, # 5 p. 1178 - 1186

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Citation Number: 9

Abstract

Figure 1. Idealized free radical oligomerization template. y1thio) methacrylate terminator.'^^ The macrocycle was obtained in 41% yield. Although methyl methacrylate produces atactic polymers, only six of the eight possible stereoisomers were detected in a 5: 5: 1998: 54 ratio. Recent developments in the control of stereoselectivity in radical additions allow control of tacticity in simple telomerization reactions. 1 Chiral pyrrolidines, oxazo-lidines, and ...