Chroman-4-one-and chromone-based sirtuin 2 inhibitors with antiproliferative properties in cancer cells

T Seifert, M Malo, T Kokkola, K Engen…

Index: Heravi, Majid M.; Ajami, Dariush; Tabar-Heydar, Kourosh Monatshefte fur Chemie, 1998 , vol. 129, # 12 p. 1305 - 1308

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Citation Number: 12

Abstract

... Volume: Page ... Because of the broad spectrum of substrates, SIRTs have been implicated as regulators in a range of physiological processes, including metabolism, cell survival and apoptosis, gene expression, and DNA repair.(12) Therefore, the enzymes have ...