The Journal of organic chemistry

Copper-Catalyzed Domino Three-Component Approach for the Assembly of 2-Aminated Benzimidazoles and Quinazolines

LQ Tran, J Li, L Neuville

Index: Deasy, Rebecca E.; Slattery, Catherine N.; Maguire, Anita R.; Kjell, Douglas P.; Hawk, Mai Khanh N.; Joo, Jung Min; Gu, Rui Lin; Moynihan, Humphrey Journal of Organic Chemistry, 2014 , vol. 79, # 8 p. 3688 - 3695

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Citation Number: 4

Abstract

... a General conditions: CuCl 2 ·H 2 O (0.2 equiv), ligand (0.2 equiv), base (2.25 equiv), O 2 (1 atm), cyanamide 14a (1.0 equiv), p-tolylboronic acid 13a, piperidine 11a, toluene, 100 °C, 24 h. b ... e ... g Reaction performed with 2.0 equiv of CuCl 2 ·H 2 O and ligand under N 2 . h ...