Russian journal of organic chemistry

Convenient synthesis of 1-aryl-1-chloro-2, 2, 2-trifluoroethyl isocyanates

NV Mel'nichenko, MV Vovk

Index: Mel'nichenko; Vovk Russian Journal of Organic Chemistry, 2008 , vol. 44, # 1 p. 149 - 150

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Citation Number: 6

Abstract

1-Aryl-1-chloro-2, 2, 2-trifluoroethyl isocyanates and their derivatives are convenient models for studying anionotropy [1] and effective electrophilic agents ensuring regioselective preparation of various trifluoromethyl-substituted heterocyclic systems [2, 3]. Fetyukhin et al.[4] described a procedure for the synthesis of 1-aryl-1-chloro-2, 2, 2-trifluoroethyl isocyanates via reaction of aryl trifluoromethyl ketone imines with trichloromethyl ...