Journal of the American Chemical Society

Preparation of Some Homologs of Papaverine

ER Shepard, JF Noth

Index: Shepard; Noth Journal of the American Chemical Society, 1950 , vol. 72, p. 4364,4366

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Citation Number: 9

Abstract

Summary Substituted 2-bromopyridines have been oxidized to the corresponding 2- bromopyridine-N-oxides by perbenzoic acid or peracetic acid. The labilized bromine atom was readily replaced by alkaline reagents; treatment with sodium hydroxide yielded the cyclic hydroxamic acid, while treatment with sodium hyctrosulfide or sodium sulfide gave the thio analog.