Chemistry–A European Journal

Synthetic Models of the Active Site of Cytochrome c Oxidase: Influence of Tridentate or Tetradentate Copper Chelates Bearing a His Tyr Linkage Mimic on Dioxygen …

JG Liu, Y Naruta, F Tani

Index: Liu, Jin-Gang; Naruta, Yoshinori; Tani, Fumito Chemistry - A European Journal, 2007 , vol. 13, # 22 p. 6365 - 6378

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Citation Number: 3

Abstract

Abstract Two synthetic models of the active site of cytochrome c oxidase–-[(L N4-OH) Cu I- Fe II (TMP)]+(1 a) and [(L N3-OH) Cu I-Fe II (TMP)]+(2 a)—have been designed and synthesized. These models each contain a heme and a covalently attached copper moiety supported either by a tetradentate N4-copper chelate or by a tridentate N3-copper chelate including a moiety that acts as a mimic of the crosslinked His-Tyr component of ...