First chemoenzymatic stereodivergent synthesis of both enantiomers of promethazine and ethopropazine

P Borowiecki, D Paprocki…

Index: SOUTHWEST RESEARCH INSTITUTE Patent: WO2003/105811 A2, 2003 ; Location in patent: Page 26 ;

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Citation Number: 5

Abstract

... Received 03 Sep 2014 Accepted 01 Dec 2014 Published 18 Dec 2014. Full Research Paper. ... of the investigated alcohol (+)-5 (L 1 /L 2 ) were compared, and their spatial location (absolute configuration ... out to be a considerable challenge as the inversion of the chiral center in the ...