Molecules

Microwave-assisted solvent-free synthesis and in vitro antibacterial screening of quinoxalines and pyrido [2, 3b] pyrazines

…, NS Gómez-Flores, OR Rodas-Suárez, J Peralta-Cruz

Index: Morales-Castellanos, J. Jesus; Ramirez-Hernandez, Karina; Gomez-Flores, Nancy S.; Rodas-Suarez, Oscar R.; Peralta-Cruz, Javier Molecules, 2012 , vol. 17, # 5 p. 5164 - 5176

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Citation Number: 15

Abstract

Abstract We report herein the microwave assisted synthesis, without solvents and catalysts, of 6-substituted quinoxalines and 7-substituted pyrido [2, 3b] pyrazines. The compounds were obtained in good yields and short reaction times using the mentioned procedure and two new structures are reported. A complete 1 H-and 13 C-NMR assignment was performed using 1D and 2D-NMR. Additionally, an in vitro screening was performed on Gram- ...