Preparation of novel anthranilic acids as antibacterial agents. Extensive evaluation of alternative amide bioisosteres connecting the A-and the B-rings

A Thorarensen, BD Wakefield, DL Romero…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 10 p. 2823 - 2827

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Citation Number: 16

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Medicinal Chemistry and Infectious Diseases Biology, Pharmacia Corporation, 301 Henrietta Street, Kalamazoo, MI 49001, USA. Received ... provide the E-alkene linker, Scheme 5. This approach used phosphonylide chemistry which we ...