Design, synthesis, and structure–activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors

T Yamashita, M Kamata, S Endo, M Yamamoto…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 21 p. 6314 - 6318

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Citation Number: 10

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. Volume 21, Issue 21, 1 November 2011, Pages 6314–6318. ... Chemical structure of CP-497485 (1a) and CP-640186 (1b) and co-crystal structure ... ...

Design, synthesis, and structure–activity relationships of s...

[Yamashita, Tohru; Kamata, Makoto; Endo, Satoshi; Yamamoto, Mitsuo; Kakegawa, Keiko; Watanabe, Hiroyuki; Miwa, Katsuhiko; Yamano, Toru; Funata, Masaaki; Sakamoto, Jyun-Ichi; Tani, Akiyoshi; Mol, Clifford D.; Zou, Hua; Dougan, Douglas R.; Sang, BiChing; Snell, Gyorgy; Fukatsu, Kohji Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 21 p. 6314 - 6318]